Structure of PDB 5fvn Chain B Binding Site BS04

Receptor Information

>5fvn Chain B (length=342) Species: 550 (Enterobacter cloacae)

AEIYNKDGNKLDLYGKVDGLHYFSDDDSQDGDQTYMRLGFKGETQVNDQL
TGYGQWEYQIQGNSGENENNSWTRVAFAGLKFGDAGSFDYGRNYGVVYDV
TSWTDVLPEFGGDTYGSDNFMQQRGNGFATYRNSDFFGLVDGLNFAVQYQ
GKNGSASGEDQTNNGRTELRQNGDGVGGSITYNLGEGFGIGTAVSSSKRT
SSQNDLTYGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGNLGWAN
KAQNFEVVAQYQFDFGLRPSVAYLQSKGKDLENGYGDQDLLKYVDVGATY
YFNKNMSTYVDYKINLLDDKEFTRNAGISTDDIVALGLVYQF

Ligand information

• Ligand ID: PO4
• InChI: InChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
• InChIKey: NBIIXXVUZAFLBC-UHFFFAOYSA-K
• SMILES:
  CACTVS 3.341: [O-][P]([O-])([O-])=O
  ACDLabs 10.04: [O-]P([O-])([O-])=O
  OpenEye OEToolkits 1.5.0: [O-]P(=O)([O-])[O-]
• Formula: O4 P
• Name: PHOSPHATE ION
• DrugBank: DB14523
• PDB chain: 5fvn Chain B Residue 406

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5fvn Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis.
• Resolution: 1.45 Å
• Binding residue (original residue number in PDB): S117 R170
• Binding residue (residue number reindexed from 1): S117 R170
• Annotation score: 3

Gene Ontology

Molecular Function

• GO:0015288 porin activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0034220 monoatomic ion transmembrane transport

Cellular Component

• GO:0009279 cell outer membrane
• GO:0016020 membrane
• GO:0046930 pore complex

External links

• PDB: RCSB:5fvn, PDBe:5fvn, PDBj:5fvn
• PDBsum: 5fvn
• PubMed: 27493217
• UniProt: Q93K99