Structure of PDB 5a50 Chain B Binding Site BS04

Receptor Information
>5a50 Chain B (length=165) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDDLLGLLRIRIKRGVNLAVRDISSSDPYVVVKMGSQKLKTRVINKDVNP
EWNEDLTLSVTDSNLTVLLTVYDHDMFSKDDKMGDAEFEIKPYIEALRMQ
LDGLPSGTIVTTVKPSRRNCLAEESRVTWVDGKLVQDLVLRLRHVECGEV
EAQLQWIDLPGSSGL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5a50 Chain B Residue 204 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5a50 Calcium-Dependent Oligomerization of Car Proteins at Cell Membrane Modulates Aba Signaling.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
H103 D109
Binding residue
(residue number reindexed from 1)
H74 D80
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008289 lipid binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006952 defense response
GO:0009651 response to salt stress
GO:0009738 abscisic acid-activated signaling pathway
GO:0009789 positive regulation of abscisic acid-activated signaling pathway
GO:1900426 positive regulation of defense response to bacterium
GO:1901002 positive regulation of response to salt stress
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5a50, PDBe:5a50, PDBj:5a50
PDBsum5a50
PubMed26719420
UniProtQ9LVH4|CAR4_ARATH Protein C2-DOMAIN ABA-RELATED 4 (Gene Name=CAR4)

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