Structure of PDB 4u7b Chain B Binding Site BS04

Receptor Information
>4u7b Chain B (length=342) Species: 7226 (Drosophila mauritiana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVPNKEQTRTVLIFCFHLKKTAAESHRMLVEAFGEQVPTVKTCERWFQRF
KSGDFDVDDKEHGKPPKRYEDAELQALLDEDDAQTQKQLAEQLEVSQQAV
SNRLREMGKIQKVGRWVPHELNERQMERRKNTCEILLSRYKRKSFLHRIV
TGDEKWIFFVNPKRKKSYVDPGQPATSTARPNRFGKKTMLCVWWDQSGVI
YYELLKPGETVNAARYQQQLINLNRALQRKRPEYQKRQHRVIFLHANAPS
HTARAVRDTLETLNWEVLPHAAYSPDLAPSDYHLFASMGHALAEQRFDSY
ESVKKWLDEWFAAKDDEFYWRGIHKLPERWEKCVASDGKYFE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4u7b Structural role of the flanking DNA in mariner transposon excision.
Resolution3.09 Å
Binding residue
(original residue number in PDB)		A25 A26 R30 K44 E47 H65 K67 P68 R71 V98 S99 Q101 R106 R167 P174 G175 F187
Binding residue
(residue number reindexed from 1)		A22 A23 R27 K41 E44 H62 K64 P65 R68 V95 S96 Q98 R103 R164 P171 G172 F184
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0003697 single-stranded DNA binding
GO:0004519 endonuclease activity
GO:0042800 histone H3K4 methyltransferase activity
GO:0044547 DNA topoisomerase binding
GO:0046872 metal ion binding
GO:0046975 histone H3K36 methyltransferase activity
Biological Process
GO:0000729 DNA double-strand break processing
GO:0006303 double-strand break repair via nonhomologous end joining
GO:0006310 DNA recombination
GO:0006338 chromatin remodeling
GO:0015074 DNA integration
GO:0031297 replication fork processing
GO:0044774 mitotic DNA integrity checkpoint signaling
Cellular Component
GO:0000793 condensed chromosome
GO:0005634 nucleus
GO:0035861 site of double-strand break

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u7b, PDBe:4u7b, PDBj:4u7b
PDBsum4u7b
PubMed25662605
UniProtQ7JQ07|MOS1T_DROMA Mariner Mos1 transposase (Gene Name=mariner\T)

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