Structure of PDB 4rkg Chain B Binding Site BS04

Receptor Information
>4rkg Chain B (length=46) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPKCRCGISGSSNTLTTCRNSRCPCYKSYNSCAGCHCVGCKNPHKE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4rkg Chain B Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4rkg Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		C525 C546 C553 C556
Binding residue
(residue number reindexed from 1)		C4 C25 C32 C35
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0061630 ubiquitin protein ligase activity
Cellular Component
GO:0072487 MSL complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4rkg, PDBe:4rkg, PDBj:4rkg
PDBsum4rkg
PubMed25452275
UniProtP50534|MSL2_DROME E3 ubiquitin-protein ligase msl-2 (Gene Name=msl-2)

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