Structure of PDB 4r8u Chain B Binding Site BS04

Receptor Information
>4r8u Chain B (length=338) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKF
GVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLS
LDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKI
ASDMNKPNGQFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCG
DVQKCDLVMLLKRFGKFGRILWERSQGIDERDVNSERLRKSVGVERTMAE
DIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQE
HVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4r8u Chain B Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4r8u Fast native-SAD phasing for routine macromolecular structure determination
Resolution2.3 Å
Binding residue
(original residue number in PDB)		D9 M10 D104
Binding residue
(residue number reindexed from 1)		D7 M8 D102
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0008296 3'-5'-DNA exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000731 DNA synthesis involved in DNA repair
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0042276 error-prone translesion synthesis
GO:0070987 error-free translesion synthesis
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r8u, PDBe:4r8u, PDBj:4r8u
PDBsum4r8u
PubMed25506719
UniProtQ47155|DPO4_ECOLI DNA polymerase IV (Gene Name=dinB)

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