Structure of PDB 4la7 Chain B Binding Site BS04

Receptor Information
>4la7 Chain B (length=298) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLMHLTGHFFGVYDGHG
GHKVADYCRDRLHFALAEEIERIKDELCRQVQWDKVFTSCFLTVDGEIEG
KIGRAVDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEA
MPLSVDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKP
YVIPEPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKK
NGAPPLAERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4la7 Chain B Residue 605 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4la7 Activation of dimeric ABA receptors elicits guard cell closure, ABA-regulated gene expression, and drought tolerance.
Resolution1.98 Å
Binding residue
(original residue number in PDB)		G247 K249
Binding residue
(residue number reindexed from 1)		G51 K53
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4la7, PDBe:4la7, PDBj:4la7
PDBsum4la7
PubMed23818638
UniProtQ9CAJ0|P2C16_ARATH Protein phosphatase 2C 16 (Gene Name=HAB1)

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