Structure of PDB 3vvk Chain B Binding Site BS04

Receptor Information

>3vvk Chain B (length=258) Species: 2257 (Natronomonas pharaonis)

VTQRELFEFVLNDPLLASSLYINIALAGLSILLFVFMTRGLDDPRAKLIA
VSTILVPVVSIASYTGLASGLTISVLEMPAGHFAEGSSVMLGGEEVDGVV
TMWGRYLTWALSTPMILLALGLLAGSNATKLFTAITFDIAMCVTGLAAAL
TTSSHLMRWFWYAISCACFIVVLYILLVEWAQDAKAAGTADIFSTLKLLT
VVMWLGYPIVWALGVEGVAVLPVGYTSWAYSALDIVAKYIFAFLLLNYLT
SNEGVVSG

Ligand information

• Ligand ID: AZI
• InChI: InChI=1S/N3/c1-3-2/q-1
• InChIKey: IVRMZWNICZWHMI-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  CACTVS 3.341
  OpenEye OEToolkits 1.5.0: [N-]=[N+]=[N-]
• Formula: N3
• Name: AZIDE ION
• ChEMBL: CHEMBL79455
• PDB chain: 3vvk Chain E Residue 304

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3vvk Large deformation of helix F during the photoreaction cycle of Pharaonis halorhodopsin in complex with azide
• Resolution: 2.3 Å
• Binding residue (original residue number in PDB): T126 W127 K256
• Binding residue (residue number reindexed from 1): T108 W109 K238
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005216 monoatomic ion channel activity
• GO:0009881 photoreceptor activity

Biological Process

• GO:0006811 monoatomic ion transport
• GO:0007602 phototransduction
• GO:0034220 monoatomic ion transmembrane transport

Cellular Component

• GO:0005886 plasma membrane
• GO:0016020 membrane

External links

• PDB: RCSB:3vvk, PDBe:3vvk, PDBj:3vvk
• PDBsum: 3vvk
• PubMed: 23442859
• UniProt: P15647|BACH_NATPH Halorhodopsin (Gene Name=hop)