Structure of PDB 3vpb Chain B Binding Site BS04

Receptor Information

>3vpb Chain B (length=282) Species: 273063 (Sulfurisphaera tokodaii str. 7)

MRVVLIVDIVRQEEKLIAKALEENKVQYDIINVAQEPLPFNKALGRYDVA
IIRPVSMYRALYSSAVLEAAGVHTINSSDVINVCGDKILTYSKLYREGIP
IPDSIIALSAEAALKAYEQRGFPLIDKPPIGSWGRLVSLIRDVFEGKTII
EHRELMGNSALKAHIVQEYIQYKGRDIRCIAIGEELLGCYARNIPPNEWR
ANVALGGTPSNIEVDEKLKETVVKAVSIVHGEFVSIDILEHPNKGYVVNE
LNDVPEFKGFMVATNINVAQKLVEYIKENYSK

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 3vpb Chain B Residue 503

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3vpb Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus
• Resolution: 1.8 Å
• Binding residue (original residue number in PDB): E250 N252
• Binding residue (residue number reindexed from 1): E250 N252
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 6.3.2.-

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0005524 ATP binding
• GO:0016874 ligase activity
• GO:0042802 identical protein binding
• GO:0043774 coenzyme F420-2 alpha-glutamyl ligase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006526 L-arginine biosynthetic process
• GO:0009085 lysine biosynthetic process
• GO:0036211 protein modification process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3vpb, PDBe:3vpb, PDBj:3vpb
• PDBsum: 3vpb
• PubMed: 23434852
• UniProt: Q970U6|ARGX_SULTO Glutamate--LysW ligase ArgX (Gene Name=argX)