Structure of PDB 3gqc Chain B Binding Site BS04

Receptor Information
>3gqc Chain B (length=440) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDCNFISNFYSHSRLHHISMWKCELTEFVNTLQRQSNGIFPGREKLKKMQ
SCIMHVDMDCFFVSVGIRNRPDLKGKPVAVTSNRGTGRAPLRPGANPQLE
WQYYQNKANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQA
VPYDFHAYKEVAQTLYETLASYTHNIEAVSCDEALVDITEILAETKLTPD
EFANAVRMEIKDQTKCAASVGIGSNILLARMATRKAKPDGQYHLKPEEVD
DFIRGQLVTNLPGVGHSMESKLASLGIKTCGDLQYMTMAKLQKEFGPKTG
QMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFTQPKEAEAFLLSLSEE
IQRRLEATGMKGKRLTLKIMVRKPGAPVETAKFGGHGICDNIARTVTLDQ
ATDNAKIIGKAMLNMFHTMKLNISDMRGVGIHVNQLVPTN
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain3gqc Chain B Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3gqc Structure of the human Rev1-DNA-dNTP ternary complex.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D423 M424 D570
Binding residue
(residue number reindexed from 1)		D57 M58 D182
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.7.-
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3gqc, PDBe:3gqc, PDBj:3gqc
PDBsum3gqc
PubMed19464298
UniProtQ9UBZ9|REV1_HUMAN DNA repair protein REV1 (Gene Name=REV1)

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