Structure of PDB 3d43 Chain B Binding Site BS04

Receptor Information

>3d43 Chain B (length=310) Species: 1421 (Lysinibacillus sphaericus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

RASQQIPWGIKAIYNNDTLTSTTGGSGINIAVLDTGVNTSHPDLVNNVEQ
CKDFTGATTPINNSCTDRNGHGTHVAGTALADGGSDQAGIYGVAPDADLW
AYKVLLDSGSGYSDDIAAAIRHAADQATATGTKTIISMSLGSSANNSLIS
SAVNYAYSKGVLIVAAAGNSGYSQGTIGYPGALPNAIAVAALENVQQNGT
YRVADYSSRGYISTAGDYVIQEGDIEISAPGSSVYSTWYNGGYNTISGTS
MATPHVSGLAAKIWAENPSLSNTQLRSNLQERAKSVDIKGGYGAAIGDDY
ASGFGFARVQ

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

3d43 Chain B Residue 316 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3d43 The crystal structures of the psychrophilic subtilisin S41 and the mesophilic subtilisin Sph reveal the same calcium-loaded state.
Resolution	0.8 Å
Binding residue (original residue number in PDB)	G181 A182 L183 A186 A188
Binding residue (residue number reindexed from 1)	G181 A182 L183 A186 A188
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	D34 H71 N169 S250
Catalytic site (residue number reindexed from 1)	D34 H71 N169 S250
Enzyme Commision number	?

Gene Ontology

	Molecular Function
GO:0004252	serine-type endopeptidase activity
GO:0008236	serine-type peptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:3d43, PDBe:3d43, PDBj:3d43
PDBsum	3d43
PubMed	18655058
UniProt	Q9S3L6

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