Structure of PDB 3ask Chain B Binding Site BS04

Receptor Information
>3ask Chain B (length=211) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLYKVNEYVDARDTNMGAWFEAQVVRVTRKEDVIYHVKYDDYPENGVVQM
NSRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRET
RTARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGSPMVDNPMRRKSG
PSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCPLSSV
PSEDEWYCPEC
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3ask Chain B Residue 506 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3ask Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Resolution2.904 Å
Binding residue
(original residue number in PDB)		C333 C336
Binding residue
(residue number reindexed from 1)		C184 C187
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3ask, PDBe:3ask, PDBj:3ask
PDBsum3ask
PubMed22837395
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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