Structure of PDB 2xnj Chain B Binding Site BS04

Receptor Information
>2xnj Chain B (length=250) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRA
YSYVNSPDNPDLEFYLVTVVYTNDAGEVVKGKLSPRLAALKPGDEVQVVS
EAAGFFVLDEVPHCETLWMLATGTAIGPYLSILRLGKDLDRFKNLVLVHA
ARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESG
ELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHGHMTAEHY
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2xnj Chain B Residue 1264 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2xnj Swapping Fad Binding Motifs between Plastidic and Bacterial Ferredoxin-Nadp(H) Reductases.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		E111 H243
Binding residue
(residue number reindexed from 1)		E110 H242
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) F36 Y52 S53 C221 E254 Y256
Catalytic site (residue number reindexed from 1) F35 Y51 S52 C220 E248 Y250
Enzyme Commision number 1.18.1.2: ferredoxin--NADP(+) reductase.
1.19.1.1: flavodoxin--NADP(+) reductase.
Gene Ontology
Molecular Function
GO:0004324 ferredoxin-NADP+ reductase activity
GO:0016491 oxidoreductase activity

View graph for
Molecular Function
External links
PDB RCSB:2xnj, PDBe:2xnj, PDBj:2xnj
PDBsum2xnj
PubMed21306142
UniProtP28861|FENR_ECOLI Flavodoxin/ferredoxin--NADP reductase (Gene Name=fpr)

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