Structure of PDB 2obe Chain B Binding Site BS04

Receptor Information
>2obe Chain B (length=906) Species: 175567 (Simian adenovirus 25) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLPQWAYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPTHD
VTTDRSQRLTLRFVPVDREDNTYSYKVRYTLAVGDNRVLDMASTYFDIRG
VLDRGPSFKPYSGTAYNSLAPKGAPNTCQWTYKATEKTYTYGNAPVQGIN
ITKDGIQLGTDTDDQPIYADKTYQPEPQVGDAEWHEKYGGRALKPDTKMK
PCYGSFAKPTNKEGGQANVKTTKEYDIDMAFFDNRSAAAAGLAPEIVLYT
ENVDLETPDTHIVYKAGTDDSSSSINLGQQAMPNRPNYIGFRDNFIGLMY
YNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSLGDRTRYFSMWN
QAVDSYDPDVRIIENHGVEDELPNYCFPLDAVGRTDTYQGIKANTTWTKD
DSVNDANEIGKGNPFAMEINIQANLWRNFLYANVALYLPDSYKYTPANVT
LPTNTNTYDYMNGRVVAPSLVDSYINIGARWSLDPMDNVNPFNHHRNAGL
RYRSMLLGNGRYVPFHIQVPQKFFAIKSLLLLPGSYTYEWNFRKDVNMIL
QSSLGNDLRTDGASISFTSINLYATFFPMAHNTASTLEAMLRNDTNDQSF
NDYLSAANMLYPIPANATNVPISIPSRNWAAFRGWSFTRLKTKETPSLGS
GFDPYFVYSGSIPYLDGTFYLNHTFKKVSITFDSSVSWPGNDRLLTPNEF
EIKRTVDGEGYNVAQCNMTKDWFLVQMLAHYNIGYQGFYVPEGYKDRMYS
FFRNFQPMSRQVVDEVNYKDYQAVTLAYQHNNSGFVGYLAPTMRQGQPYP
ANYPYPLIGKSAVTSVTQKKFLCDRVMWRIPFSSNFMSMGALTDLGQNML
YANSAHALDMNFEVDPMDESTLLYVVFEVFDVVRVHQPHRGVIEAVYLRT
PFSAGN
Ligand information
Ligand ID2HP
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-1
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0OP(=O)(O)[O-]
ACDLabs 10.04[O-]P(=O)(O)O
CACTVS 3.341O[P](O)([O-])=O
FormulaH2 O4 P
NameDIHYDROGENPHOSPHATE ION
ChEMBL
DrugBankDB02831
ZINC
PDB chain2obe Chain B Residue 1609 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2obe Structure-based identification of a major neutralizing site in an adenovirus hexon
Resolution2.1 Å
Binding residue
(original residue number in PDB)		H912 R913
Binding residue
(residue number reindexed from 1)		H889 R890
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0046718 symbiont entry into host cell
GO:0075521 microtubule-dependent intracellular transport of viral material towards nucleus
Cellular Component
GO:0019028 viral capsid
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus
GO:0043657 host cell

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2obe, PDBe:2obe, PDBj:2obe
PDBsum2obe
PubMed17108028
UniProtQ8UY79

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