Structure of PDB 1tw8 Chain B Binding Site BS04
Receptor Information
>1tw8 Chain B (length=256) Species:
727
(Haemophilus influenzae) [
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SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSD
LTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSI
ENLFEEKQNDTADILLVKDQFYELLDVKTRNISKSAQAPNIISAYKLAQT
CAKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYIN
WAAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVK
PFKKYI
Ligand information
Ligand ID
NA
InChI
InChI=1S/Na/q+1
InChIKey
FKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[Na+]
Formula
Na
Name
SODIUM ION
ChEMBL
DrugBank
DB14516
ZINC
PDB chain
1tw8 Chain B Residue 902 [
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Receptor-Ligand Complex Structure
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PDB
1tw8
Ca2+ binding in the active site of HincII: implications for the catalytic mechanism
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
D127 I142 I143
Binding residue
(residue number reindexed from 1)
D126 I141 I142
Annotation score
3
Enzymatic activity
Enzyme Commision number
3.1.21.4
: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0004519
endonuclease activity
GO:0009036
type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307
DNA restriction-modification system
View graph for
Molecular Function
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Biological Process
External links
PDB
RCSB:1tw8
,
PDBe:1tw8
,
PDBj:1tw8
PDBsum
1tw8
PubMed
15491133
UniProt
P17743
|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)
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