Structure of PDB 1h80 Chain B Binding Site BS04

Receptor Information
>1h80 Chain B (length=430) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSPKTYKDADFYVAPTQQDVNYDLVDDFGANGNDTSDDSNALQRAINAIS
RKPNGGTLLIPNGTYHFLGIQMKSNVHIRVESDVIIKPTWNGDGKNHRLF
EVGVNNIVRNFSFQGLGNGFLVDFKDSRDKNLAVFKLGDVRNYKISNFTI
DDNKTIFASILVDVTERNGRLHWSRNGIIERIKQNNALFGYGLIQTYGAD
NILFRNLHSEGGIALRMETDNLLMKNYKQGGIRNIFADNIRCSKGLAAVM
FGPHFMKNGDVQVTNVSSVSCGSAVRSDSGFVELFGCAQTARVTQKDACL
DKAKLEYGIEPGSFGTVKVFDVTARFGYNADLKQDQLDYFSTSNPMCKRV
CLPTKEQWSKQGQIYIGPSLAAVIDTTPETSKYDYDVKTFNVKRINFPVN
SHKTIDTNTESSRVCNYYGMSECSSSRWER
Ligand information
Ligand IDCL
InChIInChI=1S/ClH/h1H/p-1
InChIKeyVEXZGXHMUGYJMC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cl-]
FormulaCl
NameCHLORIDE ION
ChEMBL
DrugBankDB14547
ZINC
PDB chain1h80 Chain B Residue 1495 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1h80 The Iota-Carrageenase of Alteromonas Fortis. A Beta-Helix Fold-Containing Enzyme for the Degradation of a Highly Polyanionic Polysaccharide
Resolution1.6 Å
Binding residue
(original residue number in PDB)		F184 A185 Y218 Q222
Binding residue
(residue number reindexed from 1)		F157 A158 Y191 Q195
Annotation score3
Enzymatic activity
Enzyme Commision number 3.2.1.157: iota-carrageenase.
Gene Ontology
Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033952 iota-carrageenase activity
Biological Process
GO:0000272 polysaccharide catabolic process
GO:0071555 cell wall organization
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h80, PDBe:1h80, PDBj:1h80
PDBsum1h80
PubMed11493601
UniProtQ9F5I8|CGIA_ALTMA Iota-carrageenase (Gene Name=cgiA)

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