Structure of PDB 4v9n Chain AY Binding Site BS04

Receptor Information

>4v9n Chain AY (length=362) Species: 262724 (Thermus thermophilus HB27) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

NASRNAWKASGGIFDIPQKETRLKELERRLEDPSLWNDPEAARKVSQEAA
RLRRTVDTFRSLESDLQGLLELMEELPAEEREALKPELEEAAKKLDELYH
QTLLNFPHAEKNAILTIQPGAGGTEACDWAEMLLRMYTRFAERQGFQVEV
VDLTPGPEAGIDYAQILVKGENAYGLLSPEAGVHRLVRPSPFDASGRRHT
SFAGVEVIPEVDEEVEVVLKPEELRIDVMRASGPGGPGVNTTDSAVRVVH
LPTGITVTCQTTRSQIKNKELALKILKARLYELERKKREEELKALRGEVR
PIEWGSQIRSYVLDKNYVKDHRTGLMRHDPENVLDGDLMDLIWAGLEWKA
GRRQGTEEVEAE

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

4v9n Chain BA Residue 3676 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4v9n Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2.
Resolution	3.4 Å
Binding residue (original residue number in PDB)	G251 G252
Binding residue (residue number reindexed from 1)	G235 G236
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003747	translation release factor activity
GO:0016149	translation release factor activity, codon specific

	Biological Process
GO:0006412	translation
GO:0006415	translational termination

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:4v9n, PDBe:4v9n, PDBj:4v9n
PDBsum	4v9n
PubMed	23769667
UniProt	Q72GJ6

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