Structure of PDB 8snc Chain A Binding Site BS04

Receptor Information
>8snc Chain A (length=494) Species: 1278251 (Paramecium bursaria Chlorella virus CZ-2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAVWGISVYGVFVLGFYIAQIVFSEFNRMRLSDWISLRPDNWNATRVAVI
IAGYREDPFMFKKCLESVRDSEYGNVARLICVIDGDEEEDLKMAEIYKQV
YNDNVKKPGVVLCESENKNGSTIDSDVSKNICILQPHRGKRESLYTGFQL
ASMDPSVHAVVLIDSDTVLEKNAILEVVYPLSCDPNIKAVAGECKIWNTD
TILSMLVSWRYFSAFNVERGAQSLWKTVQCVGGPLGAYTIDIINEIKDPW
ITQTCTYGDDRRLTNEVLMRGKKIVYTPFAVGWSDSPTNVMRYIVQQTRW
SKSWCREIWYTLGSAWKHGFSGIYLAFECMYQIMYFFLVMYLFSYIAIKA
DIRAQTATVLVSTLVTIIKSSYLALRAKNLKAFYFVLYTYVYFFCMIPAR
ITAMFTMFDIVWLWAKQFLITYMWWAGVLAAGVYSIVDNWYFDWADIQYR
FALVGICSYLVFVSIVLVIYLIGKITTWNYTPLQKELIEERYLH
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain8snc Chain A Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8snc Molecular insights into hyaluronan synthesis, secretion, and length control
Resolution3.2 Å
Binding residue
(original residue number in PDB)		D201 D203
Binding residue
(residue number reindexed from 1)		D164 D166
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0050501 hyaluronan synthase activity
Biological Process
GO:0030213 hyaluronan biosynthetic process
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0085029 extracellular matrix assembly
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8snc, PDBe:8snc, PDBj:8snc
PDBsum8snc
PubMed
UniProtM1H2Q1

[Back to BioLiP]