Structure of PDB 8osi Chain A Binding Site BS04

Receptor Information
>8osi Chain A (length=400) Species: 5061,7740 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLPATHELHIFGSINGIDFDMVGQGTGNPNDGYEELNLKSTMGDLQFSPW
ILVPHIFHQYLPYPDGMSPFQAAMVDGSGYQVHRTMQFEDGATLTVNYRY
TYEGSHIKGEAQVEGTGFPADGPVMTNSLTAEAQMADSLTEEQVSEYKEL
FSLFDLDGDGQITTKELGTVMRSLDLNPSESELQDMINEVDAGGDGTIDF
PEFLTMMTREMKYRDTEEEIRELCKVFDRDNDGFIVAAELRHAMTSIGEE
LTDDEVDEMIREADQDGDGRIDYNEFVQLKMQKSGMRRLLKKAIDTVRAI
NRLREGMYFADWCVSKKTCPDDKTIVSTLKWAFITDNGKRYRSTARTTYT
FAKPMAANYLKNQPMYVFRKTELIHSKTELNFKEWQKAFTDGMGMDELYK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain8osi Chain A Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8osi FNCaMP, ratiometric green calcium indicator based on mNeonGreen protein.
Resolution2.42 Å
Binding residue
(original residue number in PDB)		D169 D171 D173 Q175 E180
Binding residue
(residue number reindexed from 1)		D155 D157 D159 Q161 E166
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0005509 calcium ion binding
GO:0030234 enzyme regulator activity
GO:0046872 metal ion binding
Biological Process
GO:0006414 translational elongation
GO:0008218 bioluminescence
GO:0051300 spindle pole body organization
Cellular Component
GO:0005823 central plaque of spindle pole body

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8osi, PDBe:8osi, PDBj:8osi
PDBsum8osi
PubMed37163937
UniProtA0A100IBH9;
A0A1S4NYF2;
A0A254U4M1

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