Structure of PDB 8gh6 Chain A Binding Site BS04

Receptor Information
>8gh6 Chain A (length=898) Species: 7091 (Bombyx mori) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GWTCQFCERTFSTNRGLGVHKRRAHPVETNTDAAPMMVKRRWHGEEIDLL
ARTEARLLAERGQCSGGDLFGALPGFGRTLEAIKGQRRREPYRALVQAHL
ARFGSTSRQKRRAEYARVQELYKKCRSRAAAEVIDGACGGVGHSLEEMET
YWRPILERVSDAPGPTPEALHALGRTQLWKPISVEEIKASRFDWRTSPGP
DGIRSGQWRAVPVHLKAEMFNAWMARGEIPEILRQCRTVFVPKVERPGGP
GEYRPISIASIPLRHFHSILARRLLACCPPDARQRGFICADGTLENSAVL
DAVLGDSRKKLRECHVAVLDFAKAFDTVSHEALVELLRLRGMPEQFCGYI
AHLYDTASTTLAVNNEMSSPVKVGRGVRQGDPLSPILFNVVMDLILASLP
ERVGYRLEMELVSALAYADDLVLLAGSKVGMQESISAVDCVGRQMGLRLN
CRKSAVLSMIPDGHRKKHHYLTERTFNIGGKPLRQVSCVERWRYLGVDFE
ASGCVTLEHSISSALNNISRAPLKPQQRLEILRAHLIPRFQHGFVLGNIS
DDRLRMLDVQIRKAVGQWLRLPADVPKAYYHAAVQDGGLAIPSVRATIPD
LIVRRFGGLDSSPWSVARAAAKSDKIRKKLRWAWKQLRRFSRVDSTTQRP
SVRLFWREHLHASVDGRELRESTRTPTSTKWIRERCAQITGRDFVQFVHT
HINALPSRIRGSRGRRGGGESSLTCRAGCKVRETTAHILQQCHRTHGGRI
LRHNKIVSFVAKAMEENKWTVELEPRLRTSVGLRKPDIIASRDGVGVIVD
VQVVSGQRSLDELHREKRNKYGNHGELVELVAGRLGLPKAECVRATSCTI
SWRGVWSLTSYKELRSIIGLREPTLQIVPILALRGSHMNWTRFNQMTS
Ligand information
>8gh6 Chain T (length=67) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ctgtgaagcgcgggtaaacggcgggagtaactatgactctcttaaggtaa
aatgcctcgtcatctaa
Receptor-Ligand Complex Structure
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PDB8gh6 Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription.
Resolution3.08 Å
Binding residue
(original residue number in PDB)
R119 R125 G126 V129 H130 V148 K149 R151 S175 R198 R418 G672 H673 S759 P781 Q897 R901 D902 Q905 A913 P915 R919 R924 R935 G957 R961 K964 F968 L1090 R1093 G1094 H1096 M1097 N1098 T1100 R1101 N1103 Q1104
Binding residue
(residue number reindexed from 1)
R9 R15 G16 V19 H20 V38 K39 R41 S65 R88 R209 G463 H464 S550 P572 Q688 R692 D693 Q696 A704 P706 R710 R715 R726 G748 R752 K755 F759 L881 R884 G885 H887 M888 N889 T891 R892 N894 Q895
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003964 RNA-directed DNA polymerase activity
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0071897 DNA biosynthetic process

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:8gh6, PDBe:8gh6, PDBj:8gh6
PDBsum8gh6
PubMed37023171
UniProtV9H052

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