Structure of PDB 8dr3 Chain A Binding Site BS04

Receptor Information
>8dr3 Chain A (length=643) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NITAQDVLDKIPSLDLSFPEGKPNCLLGLTIVFTGVLPTLERGASEALAK
RYGARVTKSISSKTSVVVLGDEAGPKKLEKIKQLKIKAIDEEGFKQLIAG
MPAEGGDGEAAEKARRKLEEQHNIATKEAELLVKKEEERSKKLAATRVSD
NVVREEDKLWTVKYAPTNLQQVCGNKGSVMKLKNWLANWENSKKNSFKHA
GKDGSGVFRAAMLYGPPGIGKTTAAHLVAQELGYDILEQNASDVRSKTLL
NAGVKNALDNMSVVGYFKHNLNGKHFVIIMDEVDGMSGGDRGGVGQLAQF
CRKTSTPLILICNERNLPKMRPFDRVCLDIQFRRPDANSIKSRLMTIAIR
EKFKLDPNVIDRLIQTTRGDIRQVINLLSTISTTTKTINHENINEISKAW
EKNIALKPFDIAHKMLDGQIYSDIGSRNFTLNDKIALYFDDFDFTPLMIQ
ENYLSTRPSVLKPGQSHLEAVAEAANCISLGDIVEKKIRSSEQLWSLLPL
HAVLSSVYPASKVAGHMAGRINFTAWLGQNSKSAKYYRLLQEIHYHTRLG
TSTDKIGLRLDYLPTFRKRLLDPFLKQGADAISSVIEVMDDYYLTKEDWD
SIMEFFVGPDVTTAIIKKIPATVKSGFTRKYNSMTHPVAIYRT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8dr3 Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		T189 K190 S193 K195 Q474 R477 F552 F587 F666
Binding residue
(residue number reindexed from 1)		T57 K58 S61 K63 Q331 R334 F409 F444 F523
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000278 mitotic cell cycle
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0051301 cell division
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8dr3, PDBe:8dr3, PDBj:8dr3
PDBsum8dr3
PubMed35939393
UniProtP38630|RFC1_YEAST Replication factor C subunit 1 (Gene Name=RFC1)

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