Structure of PDB 8d2o Chain A Binding Site BS04

Receptor Information
>8d2o Chain A (length=749) Species: 351607 (Acidothermus cellulolyticus 11B) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GTVPVTWRLGVDVGERSIGLAAVSYEEDKPKEILAAVSWIHDGGVGDERS
GASRLALRGMARRARRLRRFRRARLRDLDMLLSELGWTPLPDKNVSPVDA
WLARKRLAEEYVVDETERRRLLGYAVSHMARHRGWRNPWTTIKDLKNLPQ
PSDSWERTRESLEARYSVSLEPGTVGQWAGYLLQRAPGIRLNPTQQSLSN
ATAFETRLRQEDVLWELRCIADVQGLPEDVVSNVIDAVFCQKRPSVPAER
IRPPLPALHEATGHPVVDRNLAILRKFLSSATMRWGPPQSIVVELARGAS
ESESTGYAAVALRDRLLSYGEKNGVAQVAVFRGGVTAEARRWLDISIERL
FSRVAIFAQSTSTKRLDRRHHAVDAVVLTTLTPGVAKTLADARSRRVSAE
FWRRPSTEEPQSPAYRQWKESCSGLGDLLISTAARDSIAVAAPLRLRPTG
ALHEETLRAFSEHTVGAAWKGAELRRIVEPEVYAAFLALTDPGGRFLKVS
PSEDVLPADENRHIVLSDRVLGPRDRVKLFPDDRGSIRVRGGAAYIASFH
HARVFRWGSSHSPSFALLRVSLADLAVAGLLRDGVDVFTAELPPWTPAWR
YASIALVKAVESGDAKQVGWLVPGDELDFGPEGVTTAAGDLSMFLKYFPE
RHWVVTGFEDDKRINLKPAFLSAEQAEVLRTERSDRPDTLTEAGEILAQF
FPRCWRATVAKVLCHPGLTVIRRTALGQPRWRRGHLPYSWRPWSADPWS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8d2o Coupled catalytic states and the role of metal coordination in Cas9
Resolution2.66 Å
Binding residue
(original residue number in PDB)		E54 R55 S56 D918 R919 F934 R954 T1041 G1042 F1043 E1044 R1088
Binding residue
(residue number reindexed from 1)		E48 R49 S50 D533 R534 F549 R569 T656 G657 F658 E659 R703
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:8d2o, PDBe:8d2o, PDBj:8d2o
PDBsum8d2o
PubMed38348449
UniProtA0LWB3

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