Structure of PDB 7ynx Chain A Binding Site BS04

Receptor Information
>7ynx Chain A (length=188) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGQRGCEHYDRGCLLKAPCCDKLYTCRLCHDNNEDHQLDRFKVKEVQCIN
CEKIQHAQQTCEECSTLFGEYYCDICHLFDKDKKQYHCENCGICRIGPKE
DFFHCLKCNLCLAMNLQGRHKCIENVSRQNCPICLEDIHTSRVVAHVLPC
GHLLHRTCYEEMLKEGYRCPLCMHSALGSGSGAAAAAA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7ynx Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ynx Recognition of an Ala-rich C-degron by the E3 ligase Pirh2.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		C164 H166 C183 C186
Binding residue
(residue number reindexed from 1)		C150 H152 C169 C172
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7ynx, PDBe:7ynx, PDBj:7ynx
PDBsum7ynx
PubMed37120596
UniProtQ96PM5|ZN363_HUMAN RING finger and CHY zinc finger domain-containing protein 1 (Gene Name=RCHY1)

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