Structure of PDB 7y81 Chain A Binding Site BS04

Receptor Information
>7y81 Chain A (length=1223) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAGK
SFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFL
RKRHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSN
FDLDHDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRIT
LRNEHAKKLLLASLGFVDKLCGALCRIEVIDHNDELRKQAEVIVEAFKQN
DKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGT
ALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETTEYYSSDLFIPVT
PPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKEVINEHTSFNILLD
KENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCIEMRRIT
LKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTFPFVLRY
RGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDIKIFEWD
LNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEERECLFPYKE
NLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVYNDGNNA
IEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCIIFGNEHE
SSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDTYPLAGS
PKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGGVGYGWV
AGISIDDNVINNDYVHPGHQSPKQDHKNKNIYYPHYFLDSGSKVYREKDI
ITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGLKLQGNKPGHKNYKF
FNINGELMIPGSELRGMLRTHFEALTKSCFAIFGEDSTLSASKTLGGKLD
KALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENGPEWLITRGNNP
ERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQKQLEIRET
VQPERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGKNIAHKLG
KGKPYGFGSVKIKIDSLHTFKIKRVPQSDIREYINKGYQKLIEWSGLPQW
HVIPHIDKLYKLLWVPFLNDSKLEPDVRYPVLNEESKGYIEGSDYTYKKL
GDKDNLPYKTRVKGLTTPWSPWN
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7y81 Chain A Residue 1802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y81 Structural basis for the non-self RNA-activated protease activity of the type III-E CRISPR nuclease-protease Craspase
Resolution2.54 Å
Binding residue
(original residue number in PDB)		C491 C501 C503 C506
Binding residue
(residue number reindexed from 1)		C428 C438 C440 C443
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7y81, PDBe:7y81, PDBj:7y81
PDBsum7y81
PubMed36477448
UniProtA0A0B0EGF3

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