Structure of PDB 7y7t Chain A Binding Site BS04

Receptor Information
>7y7t Chain A (length=937) Species: 5141 (Neurospora crassa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APVAARLRNIWPKFPKWLHEAPLAVAWEVTRLFMHCKVDLEDESLKYDPS
WSTARDVTDIWKTLDAFRPEKPPNDVFVTAMTGNFESKGSAVVLSAVLDY
NPDNSPAPLYLVKLKPLMFEQGCRLTRRFGPDRFFEILIPSPTSPSVPPV
VSKQAVEEVIQWLTMGQHSLVGRQWRAFFAKDAIIKERVHFFAETGITFR
PEPVEQRTEFKVSQMLDWLLQLDNNTWQPHLKLFSRIQLGLSKTYAIMTL
EPHQIRHHKTDLLSPSGTGEVMNDGVGRMSRSVAKRIRDVLGLGDVPSAV
QGRFGSAKGMWVIDVDDTGDEDWIETYPSQRKWECDFVDKHQRTLEVRSV
ASELKSAGLNLQLLPVLEDRARDKVKMRQAIGDRLINDLQRQFSEQKHAL
NRPVEFRQWVYESYSSRATRVSHGRVPFLAGLPDSQEETLNFLMNSGFDP
KKQKYLQDIAWDLQKRKCDTLKSKLNIRVGRSAYIYMIADFWGVLEENEV
HVGFSSKFRDEEESFTLLSDCDVLVARSPAHFPSDIQRVRAVFKPELHSL
KDVIIFSTKGDVPLAKKLSGGDYDGDMAWVCWDPEIVDGFVNAEMPLEPD
LSRYLKKDKTTFKQLMASHGTGSAAKEQTTYDMIQKSFHFALQPNFLGMC
TNYKERLCYINNSVSNKPAIILSSLVGNLVDQSKQGIVFNEASWAQLRRE
LLGGALSLPDPMYKSDSWLGRGEPTHIIDYLKFSIARPAIDKELEAFHNA
MAHFWDPDLASYYTFFKEISDKSRSSALLFTTLKNRIGEVEKEYGNKSKD
PYPVRVNQVYEKWCAITPEANYDSKVIRLLELSFLADREMNTWALLRAST
AFKLYYHKSPKFVWQMAGRQLAYIKAQMTSRPGEGAPALMTAFMYAGLMP
DKKFTKQYVARLEGDGSEYPDPEVYEDGIGFTGNGDY
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7y7t Chain A Residue 1503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7y7t Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D1007 D1009
Binding residue
(residue number reindexed from 1)		D572 D574
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003968 RNA-dependent RNA polymerase activity

View graph for
Molecular Function
External links
PDB RCSB:7y7t, PDBe:7y7t, PDBj:7y7t
PDBsum7y7t
PubMed36039765
UniProtQ9Y7G6

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