Structure of PDB 7y3l Chain A Binding Site BS04

Receptor Information

>7y3l Chain A (length=57) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

KQHNCQSCGKTFSSASALQIHERTHTGEKPFGCTICGRAFTTKGNLKVHM
GTHMWNN

Ligand information

InChI=1S/Zn/q+2

PTFCDOFLOPIGGS-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Zn++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Zn+2]

Formula

Zn

Name

ZINC ION

PDB chain

7y3l Chain A Residue 1202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	7y3l Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif.
Resolution	2.5 Å
Binding residue (original residue number in PDB)	C1143 C1146 H1159 H1163
Binding residue (residue number reindexed from 1)	C33 C36 H49 H53
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:7y3l, PDBe:7y3l, PDBj:7y3l
PDBsum	7y3l
PubMed	36257403
UniProt	Q9BXA9\|SALL3_HUMAN Sal-like protein 3 (Gene Name=SALL3)

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