Structure of PDB 7vlz Chain A Binding Site BS04

Receptor Information

>7vlz Chain A (length=532) Species: 1300145 (Vibrio harveyi VHJR7)

CDVEAFTSNSSNDVLNAIKTQGASCVNALFSAESRIQEAAFESGHMYNIA
KHTTDLAKAYAGGGSDELEALFLYLRAGYYAEFYNSKVSFLSWVTPAVKE
AVDAFVNNANFYENSDPHGKVLSEVIITMDSAGLQHAYLPQVTQWLTRWD
SQYAQNWYMRNAVNGVFTILFGGQWNEQFVQTIGNQTELAKALGDFALRS
SAIGASDEFMAANAGRELGRLTKYSGSASSTVKSKLTEIFAQYEMYGRGD
AIWLGAADTVSYYADCSDYGICNFESQLKGLVLSQSYTCSPTIRILSQNM
TQDQHVAACSKMGYEEGYFHTSLETGRQPVADDYNTQLQVNIFDSSDDYG
KYAGPIFNISTNNGGMYLEGDPATPGNIPNFVAYEAPYANPDHFVWNLEH
EYVHYLDGRFDLYGGFGHPTERIVWWSEGIAEYVSKENDNQAAIDTIKDG
STFTLSEIFETSYDGFDVDRIYRWGYLAVRFMFERHKDDVNQMLIETRQG
NWANYKATINQWAILYQSEFEQWQQALVLEHH

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 7vlz Chain A Residue 702

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7vlz Crystal structure of the collagenase unit of a Vibrio collagenase from Vibrio harveyi VHJR7
• Resolution: 1.6 Å
• Binding residue (original residue number in PDB): E446 G485 L489 G491
• Binding residue (residue number reindexed from 1): E369 G408 L412 G414
• Annotation score: 4

Enzymatic activity

• Enzyme Commision number: 3.4.24.3: microbial collagenase.

Gene Ontology

Molecular Function

• GO:0004222 metalloendopeptidase activity
• GO:0008270 zinc ion binding

Biological Process

• GO:0006508 proteolysis

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:7vlz, PDBe:7vlz, PDBj:7vlz
• PDBsum: 7vlz
• UniProt: A0A8B3DGT3