Structure of PDB 7uyq Chain A Binding Site BS04
Receptor Information
>7uyq Chain A (length=347) Species:
10090
(Mus musculus) [
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PDKLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLN
TGSYYEHVKISAPNQFNVMFKLEVPRIELQEYYETGAFYLVKFPLSHFLE
GEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEE
ISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKFQG
ETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKK
EFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECL
RTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFDKL
Ligand information
>7uyq Chain J (length=18) [
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atctgtacatgtacagat
Receptor-Ligand Complex Structure
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PDB
7uyq
Structure of GTP binds to Cyclic GMP AMP synthase (cGAS) through Mg coordination
Resolution
2.57 Å
Binding residue
(original residue number in PDB)
K315 G316 R342
Binding residue
(residue number reindexed from 1)
K162 G163 R189
Enzymatic activity
Enzyme Commision number
2.7.7.86
: cyclic GMP-AMP synthase.
External links
PDB
RCSB:7uyq
,
PDBe:7uyq
,
PDBj:7uyq
PDBsum
7uyq
PubMed
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
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