Structure of PDB 7uy4 Chain A Binding Site BS04

Receptor Information
>7uy4 Chain A (length=258) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKPHSDIDLLVTV
TVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYPAK
RELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELF
DPVPEQDLFEALNETLTLWNSPPDWAGDDRNVVLTLSRIWYSAVTGKIAP
KDVAADWAMERLPAQYQPVILEARQAYLGNEEDRLASRADQLEEFVHYVK
GEITKVVG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain7uy4 Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7uy4 Characterization of the spectinomycin deactivating enzyme ANT-3,9
Resolution1.98 Å
Binding residue
(original residue number in PDB)		D43 D45
Binding residue
(residue number reindexed from 1)		D43 D45
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.47: streptomycin 3''-adenylyltransferase.
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0009012 aminoglycoside 3''-adenylyltransferase activity
GO:0016779 nucleotidyltransferase activity
GO:0070566 adenylyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:7uy4, PDBe:7uy4, PDBj:7uy4
PDBsum7uy4
PubMed
UniProtP0AG05|S3AD_ECOLX Aminoglycoside (3'') (9) adenylyltransferase (Gene Name=aadA)

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