Structure of PDB 7utt Chain A Binding Site BS04
Receptor Information
>7utt Chain A (length=351) Species:
10090
(Mus musculus) [
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KLKKVLDKLRLKRKDISEAAETVNKVVERLLRRMQKRESEFKGVEQLNTG
SYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKNPLSHFLEGE
VLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRNPEEIS
VDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDG
NSFQGETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLL
EQLKKEFQELDAFCSYHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAF
FLECLRTEKLDHYFIPKFNLFSQELIDRKSKEFLSKKIEYERNNGFPIFD
K
Ligand information
>7utt Chain J (length=18) [
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atctgtacatgtacagat
Receptor-Ligand Complex Structure
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PDB
7utt
Structure of Non-hydrolyzable ATP (ApCpp) binds to Cyclic GMP AMP synthase (cGAS) through Mn coordination
Resolution
2.04 Å
Binding residue
(original residue number in PDB)
K315 R342
Binding residue
(residue number reindexed from 1)
K160 R187
Enzymatic activity
Enzyme Commision number
2.7.7.86
: cyclic GMP-AMP synthase.
External links
PDB
RCSB:7utt
,
PDBe:7utt
,
PDBj:7utt
PDBsum
7utt
PubMed
UniProt
Q8C6L5
|CGAS_MOUSE Cyclic GMP-AMP synthase (Gene Name=Cgas)
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