Structure of PDB 7ulf Chain A Binding Site BS04

Receptor Information
>7ulf Chain A (length=247) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEVFPVEGLPLIKEGDDLAELISSRVRFEDGDVLVVCSTVISKAEGRIRR
LEEFNPSERAKEIAARIGKPAEFVQAVLEESEEVLLDFPFLLVKAKFGNV
CVNAGIDASNVEEGSLLLPPLDPDGSAEKLRRRILELTGKRVGVIITDTN
GRCFRRGVVGFAIGISGVKAMKDWIGRKDLYGRELEVTVECVADEIAAFA
NLLMGEGGDGIPAVVVRGLNVAGEGSMEEIYRSEEEDVIRRCLKRCL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain7ulf Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7ulf A Universal Mechanism for Poly-glutamylation
Resolution1.61 Å
Binding residue
(original residue number in PDB)		D109 D150
Binding residue
(residue number reindexed from 1)		D107 D148
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.2.31: coenzyme F420-0:L-glutamate ligase.
6.3.2.34: coenzyme F420-1:gamma-L-glutamate ligase.
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0016874 ligase activity
GO:0043773 coenzyme F420-0 gamma-glutamyl ligase activity
GO:0046872 metal ion binding
GO:0052618 coenzyme F420-0:L-glutamate ligase activity
GO:0052619 coenzyme F420-1:gamma-L-glutamate ligase activity
Biological Process
GO:0052645 F420-0 metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7ulf, PDBe:7ulf, PDBj:7ulf
PDBsum7ulf
PubMed
UniProtO28028|COFE_ARCFU Coenzyme F420:L-glutamate ligase (Gene Name=cofE)

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