Structure of PDB 7ubu Chain A Binding Site BS04

Receptor Information
>7ubu Chain A (length=708) Species: 4577 (Zea mays) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HEPEFIGSPVAADEARSNWPKRYGREELKARCHYRSAKVDNVVYCLGDDV
YVKAGENEADYIGRITEFFEGTDQCHYFTCRWFFRAEDTVINSLVSISVD
GHKHDPRRVFLSEEKNDNVLDCIISKVKIVHVDPNMDPKAKAQLIESCDL
YYDMSYSVAYSTFANISTRTATLLDLYSGCGGMSTGLCLGAALSGLKLET
RWAVDFNSFACQSLKYNHPQTEVRNEKADEFLALLKEWAVLCKKYVQQAD
EDSPLDKDEFVVEKLVGICYGGSDRENGIYFKVQWEGYGPEEDTWEPIDN
LSDCPQKIREFVQEGHKRKILPLPGDVDVICGGPPCQGISGFNRYRNRDE
PLKDEKNKQMVTFMDIVAYLKPKYVLMENVVDILKFADGYLGKYALSCLV
AMKYQARLGMMVAGCYGLPQFRMRVFLWGALSSMVLPKYPLPTYDVVVRG
GAPNAFSQCMVAYDETQKPSLKKALLLGDAISDLPKVQNHQPNDVMEYGG
SPKTEFQRYIRLSRKDMLDWSFGEGAGPDEGKLLDHQPLRLNNDDYERVQ
QIPVKKGANFRDLKGVRVGANNIVEWDPEIERVKLSSGKPLVPDYAMSFI
KGKSLKPFGRLWWDETVPTVVTRAEPHNQVIIHPTQARVLTIRENARLQG
FPDYYRLFGPIKEKYIQVGNAVAVPVARALGYCLGQAYLGESEGSDPLYQ
LPPSFTSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7ubu Mechanistic basis for maintenance of CHG DNA methylation in plants.
Resolution2.39 Å
Binding residue
(original residue number in PDB)
D431 E432 D437 D439 E440 F441 V442 V443 W466 Y469 E477 N481 D484 C485 P486 Q487 K488
Binding residue
(residue number reindexed from 1)
D250 E251 D256 D258 E259 F260 V261 V262 W285 Y288 E296 N300 D303 C304 P305 Q306 K307
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Gene Ontology
Molecular Function
GO:0003682 chromatin binding
GO:0008168 methyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7ubu, PDBe:7ubu, PDBj:7ubu
PDBsum7ubu
PubMed35790763
UniProtQ9AXT8|CMT1_MAIZE DNA (cytosine-5)-methyltransferase 1 (Gene Name=MET2A)

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