Structure of PDB 7tsj Chain A Binding Site BS04

Receptor Information
>7tsj Chain A (length=621) Species: 881 (Nitratidesulfovibrio vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSRSIWDDAHAMLEKAKAEGISTVWDRAAEQTPACKFCELGTTCRNCIMG
PCRIANRKDGKMRLGVCGADADVIVARNFGRFIAGGAAGHSDHGRDLIET
LEAVAEGKAPGYTIRDVAKLRRIAAELGVADAATRPAHDVAADLVTICYN
DFGSRRNALAFLARAPQVRRDLWQRLGMTPRGVDREIAEMMHRTHMGCDN
DHTSLLVHAARTALADGWGGSMIGTELSDILFGTPRPRQSTVNLGVLRKD
AVNILVHGHNPVVSEMILAATREPAVRQAAQDAGAADINVAGLCCTGNEL
LMRQGIPMAGNHLMTELAIVTGAADAIVADYQCIMPSLVQIAACYHTRFV
TTSPKGRFTGATHVEVHPHNAQERCREIVMLAIDAYTRRDPARVDIPSQP
VSIMSGFSNEAILEALGGTPKPLIDAVVAGQIRGFVGIVGCNNPKIRQDS
ANVTLTRELIRRDIMVLATGCVTTAAGKAGLLVPEAASKAGEGLAAVCRS
LGVPPVLHMGSCVDNSRILQLCALLATTLGVDISDLPVGASSPEWYSEKA
AAIAMYAVASGIPTHLGLPPNILGSENVTAMALHGLQDVVGAAFMVEPDP
VKAADMLEAHIVARRARLGLT
Ligand information
Ligand IDXE
InChIInChI=1S/Xe
InChIKeyFHNFHKCVQCLJFQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Xe]
FormulaXe
NameXENON
ChEMBLCHEMBL1236802
DrugBankDB13453
ZINC
PDB chain7tsj Chain A Residue 704 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7tsj Visualizing the gas channel of a monofunctional carbon monoxide dehydrogenase.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		F86 A558 F601
Binding residue
(residue number reindexed from 1)		F79 A551 F594
Annotation score1
Enzymatic activity
Enzyme Commision number 1.2.7.4: anaerobic carbon-monoxide dehydrogenase.
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004601 peroxidase activity
GO:0016151 nickel cation binding
GO:0016491 oxidoreductase activity
GO:0043885 anaerobic carbon-monoxide dehydrogenase activity
GO:0046872 metal ion binding
GO:0050418 hydroxylamine reductase activity
GO:0051537 2 iron, 2 sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006091 generation of precursor metabolites and energy
GO:0042542 response to hydrogen peroxide
GO:0098869 cellular oxidant detoxification

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7tsj, PDBe:7tsj, PDBj:7tsj
PDBsum7tsj
PubMed35278753
UniProtQ72A99

[Back to BioLiP]