Structure of PDB 7m0c Chain A Binding Site BS04

Receptor Information
>7m0c Chain A (length=332) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LDKWVCAQPSSQKATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINA
LKSFHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHISESVPVL
ELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQASLTTQQAIGLKHYSDFLE
RMPREEATEIEQTVQKAAQAFNSGLLCVACGSYRRGKATCGDVDVLITHP
DGRSHRGIFSRLLDSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRR
HRRLDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSEHALSTA
VVRPGRVLPTPTEKDVFRLLGLPYREPAERDW
Ligand information
Receptor-Ligand Complex Structure
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PDB7m0c Comprehensive structural survey of DNA double-strand break synapsis by DNA Polymerase Lambda
Resolution2.65 Å
Binding residue
(original residue number in PDB)		W274 R275 Y279 P303 G304 G306 R308 M309 K312
Binding residue
(residue number reindexed from 1)		W39 R40 Y44 P68 G69 G71 R73 M74 K77
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
4.2.99.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034061 DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7m0c, PDBe:7m0c, PDBj:7m0c
PDBsum7m0c
PubMed
UniProtQ9UGP5|DPOLL_HUMAN DNA polymerase lambda (Gene Name=POLL)

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