Structure of PDB 7esi Chain A Binding Site BS04

Receptor Information
>7esi Chain A (length=532) Species: 1300145 (Vibrio harveyi VHJR7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CDVEAFTSNSSNDVLNAIKTQGASCVNALFSAESRIQEAAFESGHMYNIA
KHTTDLAKAYAGGGSDELEALFLYLRAGYYAEFYNSKVSFLSWVTPAVKE
AVDAFVNNANFYENSDPHGKVLSEVIITMDSAGLQHAYLPQVTQWLTRWD
SQYAQNWYMRNAVNGVFTILFGGQWNEQFVQTIGNQTELAKALGDFALRS
SAIGASDEFMAANAGRELGRLTKYSGSASSTVKSKLTEIFAQYEMYGRGD
AIWLGAADTVSYYADCSDYGICNFESQLKGLVLSQSYTCSPTIRILSQNM
TQDQHVAACSKMGYEEGYFHTSLETGRQPVADDYNTQLQVNIFDSSDDYG
KYAGPIFNISTNNGGMYLEGDPATPGNIPNFVAYEAPYANPDHFVWNLEH
EYVHYLDGRFDLYGGFGHPTERIVWWSEGIAEYVSKENDNQAAIDTIKDG
STFTLSEIFETSYDGFDVDRIYRWGYLAVRFMFERHKDDVNQMLIETRQG
NWANYKATINQWAILYQSEFEQWQQALVLEHH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain7esi Chain A Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7esi Structure of Vibrio collagenase VhaC provides insight into the mechanism of bacterial collagenolysis.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		E446 G485 L489 G491
Binding residue
(residue number reindexed from 1)		E369 G408 L412 G414
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7esi, PDBe:7esi, PDBj:7esi
PDBsum7esi
PubMed35091565
UniProtA0A8B3DGT3

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