Structure of PDB 7bee Chain A Binding Site BS04

Receptor Information

>7bee Chain A (length=378) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MLSPKAATLAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLG
GKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRL
YGPSSVSFAEDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGK
LPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGV
TMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKL
LTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNK
ADLSRMSGKKDLYLASVFHATAFEWDTEGNPFDQDIYGREELRSPKLFYA
DHPFIFLVRDTQSGSLLFIGRLVRPKGD

Ligand information

>7bee Chain G (length=19) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

PPGPPGPPGPRGFPGPPGP

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7bee Collagen's primary structure determines collagen:HSP47 complex stoichiometry.
Resolution	1.939 Å
Binding residue (original residue number in PDB)	Q171 S172
Binding residue (residue number reindexed from 1)	Q137 S138

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005518	collagen binding

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005783	endoplasmic reticulum

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7bee, PDBe:7bee, PDBj:7bee
PDBsum	7bee
PubMed	34487762
UniProt	A0A8I3N7V2

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