Structure of PDB 6xny Chain A Binding Site BS04

Receptor Information
>6xny Chain A (length=550) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEK
VLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFR
YDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEK
HGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSVLCCKPLCLM
LADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYD
EKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYE
VWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIF
QLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMMMNGNFARKLM
TQETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQ
YSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWAS
EGNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHNA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xny Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		K645 S648 L650 N852 R855 P891 R894 S895 E901 E959
Binding residue
(residue number reindexed from 1)		K187 S190 L192 N394 R397 P433 R436 S437 E443 E501
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6xny, PDBe:6xny, PDBj:6xny
PDBsum6xny
PubMed32945578
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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