Structure of PDB 6wm5 Chain A Binding Site BS04

Receptor Information

>6wm5 Chain A (length=337) Species: 224325,557599

MRLAYVKNHEIYGEKLLGLTLRERIEKTLQRAGFDVRFFDELSLEEAEDY
LIILEPVLILERDLLLEGRKILVSDGFTVGYFFGGDFRTVFDGNLQSSIE
KYLSLNNLESYEIWAIKLSNDNLKTAEKLLLSSLISRAAFARITLPLARA
LLRIGLTPDAVTIIGTTASVAGALVLFPMGKLFPGACVVWFFVLFDMLDG
AMARLRSGGTRFGAVLDAACDRISDGAVFSGLLWWIAFGMRDRLLVVATL
TCLVTSQVISYIKARAEASGLRGDGGIIERPERLIIVLVGAGVSDFPFIA
WPPALPVAMWVLAVASVITLGQRLHTVWTSPGATDRI

Ligand information

• Ligand ID: GOL
• InChI: InChI=1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2
• InChIKey: PEDCQBHIVMGVHV-UHFFFAOYSA-N
• SMILES:
  OpenEye OEToolkits 1.7.0: C(C(CO)O)O
  ACDLabs 12.01
  CACTVS 3.370: OCC(O)CO
• Formula: C3 H8 O3
• Name: GLYCEROL;
  GLYCERIN;
  PROPANE-1,2,3-TRIOL
• ChEMBL: CHEMBL692
• DrugBank: DB09462
• ZINC: ZINC000000895048
• PDB chain: 6wm5 Chain A Residue 328

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6wm5 Structural and Functional Characterization of Phosphatidylinositol-Phosphate Biosynthesis in Mycobacteria.
• Resolution: 1.961 Å
• Binding residue (original residue number in PDB): A176 A180
• Binding residue (residue number reindexed from 1): A304 A308
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number:
  2.7.8.-

Gene Ontology

Molecular Function

• GO:0016780 phosphotransferase activity, for other substituted phosphate groups

Biological Process

• GO:0008654 phospholipid biosynthetic process

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:6wm5, PDBe:6wm5, PDBj:6wm5
• PDBsum: 6wm5
• PubMed: 32389689
• UniProt: O27985;
  U5WZP7