Structure of PDB 6v3c Chain A Binding Site BS04

Receptor Information
>6v3c Chain A (length=250) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTVSTIFLVVVLYLIIGATVFKALEQPQEISQRTTIVIQREKFLRAHPCV
SDQELDELIQQIVAADNSHWDLGSSFFFAGTVITTIGFGNISPRTEGGKI
FCIIYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEQTKIRIISTIIFIL
FGCVLFVALPAVIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSLDFY
KPVVWFWILVGLAYFAAVLSMIGDWLRVIAKKTKEAVGEFRAHAAEWTAN
Ligand information
Ligand IDK
InChIInChI=1S/K/q+1
InChIKeyNPYPAHLBTDXSSS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[K+]
FormulaK
NamePOTASSIUM ION
ChEMBLCHEMBL1233793
DrugBankDB01345
ZINC
PDB chain6v3c Chain B Residue 404 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6v3c Polynuclear Ruthenium Amines Inhibit K2PChannels via a "Finger in the Dam" Mechanism.
Resolution3.51 Å
Binding residue
(original residue number in PDB)		G144 F145 G146 G253 F254 G255
Binding residue
(residue number reindexed from 1)		G87 F88 G89 G187 F188 G189
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6v3c, PDBe:6v3c, PDBj:6v3c
PDBsum6v3c
PubMed32059793
UniProtP97438|KCNK2_MOUSE Potassium channel subfamily K member 2 (Gene Name=Kcnk2)

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