Structure of PDB 6szi Chain A Binding Site BS04

Receptor Information
>6szi Chain A (length=1276) Species: 1245 (Leuconostoc mesenteroides) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSDPITGGHYENHNGYFVYIDASGKQVTGLQNIDGNLQYFDDNGYQVKGS
FRDVNGKHIYFDSVTGKASSNVDIVNGKAQGYDAQGNQLKKSYVADSSGQ
TYYFDGNGQPLIGLQTIDGNLQYFNQQGVQIKGGFQDVNNKRIYFAPNTG
NAVANTEIINGKLQGRDANGNQVKNAFSKDVAGNTFYFDANGVMLTGLQT
ISGKTYYLDEQGHLRKNYAGTFNNQFMYFDADTGAGKTAIEYQFDQGLVS
QSNENTPHNAAKSYDKSSFENVDGYLTADTWYRPTDILKNGDTWTASTET
DMRPLLMTWWPDKQTQANYLNFMSSKGLGITTTYTAATSQKTLNDAAFVI
QTAIEQQISLKKSTEWLRDAIDSFVKTQANWNKQTEDEAFDGLQWLQGGF
LAYQDDSHRTPNTDSGNNRKLGRQPINIDGSKDTTDGKGSEFLLANDIDN
SNPIVQAEQLNWLHYLMNFGSITGNNDNANFDGIRVDAVDNVDADLLKIA
GDYFKALYGTDKSDANANKHLSILEDWNGKDPQYVNQQGNAQLTMDYTVT
SQFGNSLTHGANNRSNMWYFLDTGYYLNGDLNKKIVDKNRPNSGTLVNRI
ANSGDTKVIPNYSFVRAHDYDAQDPIRKAMIDHGIIKNMQDTFTFDQLAQ
GMEFYYKDQENPSGFKKYNDYNLPSAYAMLLTNKDTVPRVYYGDMYLEGG
QYMEKGTIYNPVISALLKARIKYVSGGQTMATDSSGKDLKDGETDLLTSV
RFGKGIMTSDQTTTQDNSQDYKNQGIGVIVGNNPDLKLNNDKTITLHMGK
AHKNQLYRALVLSNDSGIDVYDSDDKAPTLRTNDNGDLIFHKTNTFVKQD
GTIINYEMKGSLNALISGYLGVWVPVGASDSQDARTVATESSSSNDGSVF
HSNAALDSNVIYEGFSNFQAMPTSPEQSTNVVIATKANLFKELGITSFEL
APQYRSSGDTNYGGMSFLDSFLNNGYAFTDRYDLGFNKADGNPNPTKYGT
DQDLRNAIEALHKNGMQAIADWVPDQIYALPGKEVVTATRVDERGNQLKD
TDFVNLLYVANTKSSGVDYQAKYGGEFLDKLREEYPSLFKQNQVSTGQPI
DASTKIKQWSAKYMNGTNILHRGAYYVLKDWATNQYFNIAKTNEVFLPLQ
LQNKDAQTGFISDASGVKYYSISGYQAKDTFIEDGNGNWYYFDKDGYMVR
SQQGENPIRTVETSVNTRNGNYYFMPNGVELRKGFGTDNSGNVYYFDDQG
KMVRDKYINDDANNFYHLNVDGTMSR
Ligand information
Ligand IDGLC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL423707
DrugBank
ZINCZINC000003861213
PDB chain6szi Chain D Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6szi A specific oligosaccharide-binding site in the alternansucrase catalytic domain mediates alternan elongation.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		Y241 Q278 K280 T297
Binding residue
(residue number reindexed from 1)		Y93 Q130 K132 T149
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.5: dextransucrase.
Gene Ontology
Molecular Function
GO:0046527 glucosyltransferase activity
Biological Process
GO:0009250 glucan biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6szi, PDBe:6szi, PDBj:6szi
PDBsum6szi
PubMed32409580
UniProtQ9RE05

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