Structure of PDB 6ot3 Chain A Binding Site BS04

Receptor Information
>6ot3 Chain A (length=357) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQPDVWNEPERAQA
LGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAELDA
LEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRW
AESRGFKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKS
PFDSGGRRHTSFSSAFVYPEVDDDIDIEINPADLRIDVYRTSGAGGQHVN
RTESAVRITHIPTGIVTQCQNDRSQHKNKDQAMKQMKAKLYELEMQKKNA
EKQAMEDNKSDIGWGSQIRSYVLDDSRIKDLRTGVETRNTQAVLDGSLDQ
FIEASLK
Ligand information
>6ot3 Chain 5 (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgggguugagcagccugguagcucgucgggcugaaaacccgaagaucgu
cgguucaaauccggcccccgcaacca
<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>.....<<
<<<.......>>>>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB6ot3 The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		E172 D277 R278
Binding residue
(residue number reindexed from 1)		E167 D272 R273
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003747 translation release factor activity
GO:0016149 translation release factor activity, codon specific
Biological Process
GO:0006412 translation
GO:0006415 translational termination
GO:0075523 viral translational frameshifting
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6ot3, PDBe:6ot3, PDBj:6ot3
PDBsum6ot3
PubMed31189921
UniProtP07012|RF2_ECOLI Peptide chain release factor RF2 (Gene Name=prfB)

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