Structure of PDB 6lrd Chain A Binding Site BS04

Receptor Information
>6lrd Chain A (length=698) Species: 1299 (Deinococcus radiodurans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPAHWLLAPPASRDALLATMREWQVSPPVAQVLCGRDLRTELLALPLELT
PNPALREAARHIVAAVREGKRIRIHGDYDADGVSATATLVLGLRAIGANV
HGFIPHRLNEGYGIHPDRVPEHAAAADLVVTVDCGVSNLDEVKSLLATGT
EVVVTDHHAPGENFPECLVVHPHLTPDYDPDRHNLTGAGVAYHLLWAVYE
ELGRPEPRALLPLATLGTVADVAPLLGENRALVRAGLAEMARTELPGLRA
LMNEKRVRQPTARDVAFILAPRINAAGRMGEADRALELLTTPSDHEAKSL
AAYLEIRNQERRKIQDDMFAQALQLADPNDPALVLTHDDWHAGVMGIVAS
KLVETFNRPVYIVAQGKGSVRSTPGISAVQGLRESRDLLGRFGGHPGAAG
FSLDPQNFGALRERIHGYVRQFPTPVPAVRLDAPLPVAALTPELLSELSI
LEPFGEGNPRPLWHLRGPLTDTRLVGKQGDVLQFRFGGVKGMKYSERDDA
AGERDVAAELALNTSLELHAAALRPLAPLALAGTEEGLPTLPRLNPREAM
TFLKTGAAAYAEQGVATYLRDNVPGLTLLDTNAPHPGGDLILYGLPPESA
LRRWLHEAQEQGGRVAFALGPKTLAELDAALTLAKLLPDSHTEAAQEAAA
DAYRSWQWAHHYRVLNDAGWSASVYAMLGLPVPAALPKAAEALALAAG
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6lrd Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6lrd Participation of RecJ in the base excision repair pathway of Deinococcus radiodurans.
Resolution1.90134 Å
Binding residue
(original residue number in PDB)		D79 D81 D135
Binding residue
(residue number reindexed from 1)		D77 D79 D133
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004527 exonuclease activity
GO:0008409 5'-3' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:6lrd, PDBe:6lrd, PDBj:6lrd
PDBsum6lrd
PubMed32870272
UniProtD0EM60

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