Structure of PDB 6go7 Chain A Binding Site BS04

Receptor Information
>6go7 Chain A (length=338) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KISQYACQRRTTLNNYNQLFTDALDILAENDELRENEGSCLAFMRASSVL
KSLPFPITSMKDTEGIPCLGDKVKSIIEGIIEDGESSEAKAVLNDERYKS
FKLFTSVFGVGLKTAEKWFRMGFRTLSKIQSDKSLRFTQMQKAGFLYYED
LVSCVNRPEAEAVSMLVKEAVVTFLPDALVTMTGGFRRGKMTGHDVDFLI
TSPEATEDEEQQLLHKVTDFWKQQGLLLYHQYHRSFERSFCILKLDHGRV
HSGKGWKAIRVDLVMCPYDRRAFALLGWTGSRQFERDLRRYATHERKMML
DNHALYDRTKRVFLEAESEEEIFAHLGLDYIEPWERNA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6go7 Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		K265 T286 Q287 H381 R382
Binding residue
(residue number reindexed from 1)		K117 T138 Q139 H233 R234
Enzymatic activity
Enzyme Commision number 2.7.7.31: DNA nucleotidylexotransferase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.11.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034061 DNA polymerase activity
Biological Process
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:6go7, PDBe:6go7, PDBj:6go7
PDBsum6go7
PubMed31138645
UniProtP09838|TDT_MOUSE DNA nucleotidylexotransferase (Gene Name=Dntt);
Q9JIW4|DPOLM_MOUSE DNA-directed DNA/RNA polymerase mu (Gene Name=Polm)

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