Structure of PDB 6fwf Chain A Binding Site BS04

Receptor Information
>6fwf Chain A (length=712) Species: 662598 (Neisseria meningitidis alpha14) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GQYKKLWYLLFAVLAVCFTILGYMGSEVYKKPYPEQVVSASGKVLMAKDD
ILAGQSAWQTTGGMEVGSVLGHGAYQAPDWTADWLHRELSAWLDLTAQQT
YGKKFDEVSPEEQAVLKTRLADEYRNQSRIDGSVVISDTRVKAIESILPY
YYGDDPNTLPSQEAREKLFDFFFWTSWSASTNRPDETFTYTNNWPHEPLI
NNVPTTENYMWSFTSVVLLLMGIGLLMWGYSFLTEVEVPTEDPISKVQSQ
KALGKYVFLTVALFVVQVLLGGLTAHYTVEGQGFYGIDEALGFEMSDWFP
YALTRTWHIQSAIFWIATGFLTAGLFLAPIVNGGKDPKFQRAGVNFLYIA
LFIVVGGSYAGNFFALTHILPPEFNFWFGHQGYEYLDLGRFWQLLLMVGL
LLWLFLMLRCTVSAFKEKGVDKNLLAIFVASMVGVGVFYAPGLFYGEKSP
IAVMEYWRWWVVHLWVEGFFEVFATAAFAFVFYNMGFVAAAAIFMLGGVP
GTLHHLYFSGSTSASMAIGACFSALEVVPLVLLGREAYEHWSYQHLSEWA
KRLRWPLMCFVAVAFWNMIGAGVFGFLINPPISLFYIQGLNTSAVHAHAA
LFGVYGFLALGFVLLARYLKPNVQFDDKLMTWGFWLLNGGLVGMIAISLL
PVGVIQAYASITHGLWYARSEEFLQMEILDTLRWVRTAADLIFIGGAICV
AIQATKIVFGRD
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain6fwf Chain A Residue 1004 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6fwf Characterization of the quinol-dependent nitric oxide reductase from the pathogen Neisseria meningitidis, an electrogenic enzyme.
Resolution4.2 Å
Binding residue
(original residue number in PDB)		H490 H541 H542
Binding residue
(residue number reindexed from 1)		H463 H504 H505
Annotation score5
Enzymatic activity
Enzyme Commision number 1.7.99.7: Transferred entry: 1.7.2.5.
Gene Ontology
Molecular Function
GO:0004129 cytochrome-c oxidase activity
GO:0009486 cytochrome bo3 ubiquinol oxidase activity
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0009060 aerobic respiration
GO:0015990 electron transport coupled proton transport
GO:0022904 respiratory electron transport chain
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6fwf, PDBe:6fwf, PDBj:6fwf
PDBsum6fwf
PubMed29483528
UniProtC6S880

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