Structure of PDB 6eet Chain A Binding Site BS04

Receptor Information
>6eet Chain A (length=443) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDD
VQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSS
ATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVY
SIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANL
RVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKAT
DRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFK
FQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTE
ILDRYVQEQIPGAKVVVESIGARRHGDAYSLEDYSKCDLTVYAIDPQTNR
AIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6eet Chain A Residue 1409 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6eet Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution3.23 Å
Binding residue
(original residue number in PDB)		E1026 E1077 D1115 E1116 D1118 D1151
Binding residue
(residue number reindexed from 1)		E128 E179 D217 E218 D220 D253
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6eet, PDBe:6eet, PDBj:6eet
PDBsum6eet
PubMed32963095
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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