Structure of PDB 6cij Chain A Binding Site BS04

Receptor Information
>6cij Chain A (length=614) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRARNE
HRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGR
QIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASS
VDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVV
VKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEP
KPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEMGGI
PRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNLVFH
SITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSIDAL
HCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLK
PIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKPVWR
SSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVP
EIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHHWLY
TSKYLQKFMNAHNA
Ligand information
Receptor-Ligand Complex Structure
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PDB6cij Cracking the DNA Code for V(D)J Recombination.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		H445 K645 N647 S648 E649 R855 R894 S896 E901 E959
Binding residue
(residue number reindexed from 1)		H51 K251 N253 S254 E255 R461 R500 S502 E507 E565
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cij, PDBe:6cij, PDBj:6cij
PDBsum6cij
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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