Structure of PDB 6bv6 Chain A Binding Site BS04

Receptor Information
>6bv6 Chain A (length=470) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPEALLKQKLDMCSKKGDVLEALRLYDEARRNGVQLSQYHYNVLLYVCSL
AEASSPNPGLSRGFDIFKQMIVDKVVPNEATFTNGARLAVAKDDPEMAFD
MVKQMKAFGIQPRLRSYGPALFGFCRKGDADKAYEVDAHMVESEVVPEEP
ELAALLKVSMDTKNADKVYKTLQRLRDLVRQVSKSTFDMIEEWFKSEVAT
KTGVKKWDVKKIRDAVVSGGGGWHGQGWLGTGKWNVKRTEMDENGVCKCC
KEKLVCIDINPVETETFAASLTRLACEREVKANFNQFQEWLERHGPFDAV
IDGANMGLVNQRSFSFFQLNNTVQRCQQISPSKRLPLVILHKSRVNATYP
KNRALLEKWKNAGALYATPPGSNDDWYWLYAAVSCKCLLVTNDEMRDHLF
QLLGNSFFPRWKEKHQVRISVTREDGLKLNMPPPYSIVIQESEDGTWHVP
MSVEDDLQTSRQWLCAKRSK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6bv6 Chain A Residue 604 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6bv6 Inhibition of protein-only RNase P with Gambogic acid and Juglone
Resolution2.2 Å
Binding residue
(original residue number in PDB)		C344 C347 H548 C565
Binding residue
(residue number reindexed from 1)		C247 C250 H448 C465
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.26.5: ribonuclease P.
External links
PDB RCSB:6bv6, PDBe:6bv6, PDBj:6bv6
PDBsum6bv6
PubMed
UniProtQ66GI4|PRRP1_ARATH Proteinaceous RNase P 1, chloroplastic/mitochondrial (Gene Name=PRORP1)

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