Structure of PDB 6bmm Chain A Binding Site BS04

Receptor Information
>6bmm Chain A (length=290) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLV
AFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEI
LRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHC
PWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRA
KFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDG
NGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRL
Ligand information
Ligand IDDYD
InChIInChI=1S/C6H14O2/c1-5(7)3-4-6(2)8/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1
InChIKeyOHMBHFSEKCCCBW-WDSKDSINSA-N
SMILES
SoftwareSMILES
CACTVS 3.385C[C@H](O)CC[C@H](C)O
CACTVS 3.385C[CH](O)CC[CH](C)O
ACDLabs 12.01
OpenEye OEToolkits 2.0.6		CC(CCC(C)O)O
OpenEye OEToolkits 2.0.6C[C@@H](CC[C@H](C)O)O
FormulaC6 H14 O2
Name(2S,5S)-hexane-2,5-diol
ChEMBL
DrugBank
ZINCZINC000000388717
PDB chain6bmm Chain A Residue 408 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6bmm Fatty acyl recognition and transfer by an integral membraneS-acyltransferase.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		W267 F271 W278
Binding residue
(residue number reindexed from 1)		W261 F265 W272
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.225: protein S-acyltransferase.
Gene Ontology
Molecular Function
GO:0016409 palmitoyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:6bmm, PDBe:6bmm, PDBj:6bmm
PDBsum6bmm
PubMed29326245
UniProtQ5W0Z9|ZDH20_HUMAN Palmitoyltransferase ZDHHC20 (Gene Name=ZDHHC20)

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