Structure of PDB 5zln Chain A Binding Site BS04

Receptor Information

>5zln Chain A (length=751) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TLPAFLPCELKPHGLVDCNWLFLKSVPRFSAAASCSNITRLSLISNRIHH
LHNSDFVHLSNLRQLNLKWNCPPTGLSPLHFSCHMTIEPRTFLAMRTLEE
LNLSYNGITTVPRLPSSLVNLSLSHTNILVLDANSLAGLYSLRVLFMDGN
CYYKNPCTGAVKVTPGALLGLSNLTHLSLKYNNLTKVPRQLPPSLEYLLV
SYNLIVKLGPEDLANLTSLRVLDVGGNCRRCDHAPNPCIECGQKSLHLHP
ETFHHLSHLEGLVLKDSSLHTLNSSWFQGLVNMSVLDLSENFLYESIQHT
NAFQNLTRLRKLNLSFNYRKKVSFARLHLASSFKNLVSLQELNMNGIFFR
SLNKYTLRWLADLPKLHTLHLQMNFINQAQLSIFGTFRALRFVDLSDNRI
SGPSTKNFMDRCKNFKFTMDLSRNNLVTIKPEMFVQLSRLQCLSLSHNSI
AQAVQGSQFLPLTNLQVLDLSHNKLDLYHWKSFSELPQLQALDLSYNSQP
FSMKGIGHNFSFVAHLSMLHSLSLAHNDIHTRVSSHLNSNSVRFLDFSGN
GMGRMWDEGGLYLHFFQGLSGLLKLDLSQNNLHILRPQNLDNLPKSLKLL
SLRDNYLSFFQWTSLSFLPNLEVLDLAGNQLKALTNGTLPNGTLLQKLDV
SSNSIVSVVPAFFALAVELKEVNLSHNILKTVDRSWFGPIVMNLTVLDVR
SNPLHCACGAAFVDLLLEVQTKVPGLANGVKCGSPGQLQGRSIFAQDLRL
C

Ligand information

>5zln Chain F (length=4) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tcgc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5zln Structural basis for species-specific activation of mouse Toll-like receptor 9
Resolution	2.3 Å
Binding residue (original residue number in PDB)	D535 Y537 G566 H567 R591 V592
Binding residue (residue number reindexed from 1)	D476 Y478 G507 H508 R532 V533

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:5zln, PDBe:5zln, PDBj:5zln
PDBsum	5zln
PubMed	29961984
UniProt	Q9EQU3\|TLR9_MOUSE Toll-like receptor 9 (Gene Name=Tlr9)

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