Structure of PDB 5ubh Chain A Binding Site BS04

Receptor Information
>5ubh Chain A (length=217) Species: 195099 (Campylobacter jejuni RM1221) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTRLRIAIQKSGRLSKESIELLSECGVKMHIHEQSLIAFSTNLPIDILRV
RDDDIPGLIFDGVVDLGIIGENVLEENELERQSLGENPSYKLLKKLDFGY
CRLSLALPQENKFQNLKDFEGLRIATSYPQLLKRFMKENGINYKNCTLTG
SVEVAPRANLADAICDLVSSGATLQANNLKEVKVIYESRACLIQKENALS
KEKQALVDKIMLRVAGV
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain5ubh Chain A Residue 304 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5ubh A dimeric catalytic core relates the short and long forms of ATP-phosphoribosyltransferase.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		V171 S172 S173 T176
Binding residue
(residue number reindexed from 1)		V168 S169 S170 T173
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.2.17: ATP phosphoribosyltransferase.
Gene Ontology
Molecular Function
GO:0003879 ATP phosphoribosyltransferase activity
Biological Process
GO:0000105 L-histidine biosynthetic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ubh, PDBe:5ubh, PDBj:5ubh
PDBsum5ubh
PubMed29208762
UniProtQ5HSJ4|HIS1_CAMJR ATP phosphoribosyltransferase (Gene Name=hisG)

[Back to BioLiP]