Structure of PDB 5o6d Chain A Binding Site BS04

Receptor Information
>5o6d Chain A (length=527) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVAV
TASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENIG
ALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPVS
KPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDET
EREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAID
GGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKVI
EFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASRK
SSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNSA
GKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAWS
LSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTRI
KAHQKVIDFYLTLSSAESAYKQLEADE
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5o6d Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5o6d Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase.
Resolution3.283 Å
Binding residue
(original residue number in PDB)		S265 G709
Binding residue
(residue number reindexed from 1)		S29 G458
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5o6d, PDBe:5o6d, PDBj:5o6d
PDBsum5o6d
PubMed29202194
UniProtP07271|PIF1_YEAST ATP-dependent DNA helicase PIF1 (Gene Name=PIF1)

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